BDBM300519 N-[5-(2-fluorophenyl)-1,3,4-thiadiazol-2-yl]-3-({[1-(morpholin-4-yl)cyclopropyl]carbonyl}amino)-4-(trifluoromethoxy)benzamide::US10130633, Example 89

SMILES O=C(Nc2nnc(c1ccccc1F)s2)c5ccc(OC(F)(F)F)c(NC(=O)C4(N3CCOCC3)CC4)c5

InChI Key InChIKey=UIRJNEQFJAASIK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 300519   

TargetProtein Wnt-3a(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300519(N-[5-(2-fluorophenyl)-1,3,4-thiadiazol-2-yl]-3-({[...)
Affinity DataIC50: 216nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2019
Entry Details
US Patent

TargetProtein Wnt-3a(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300519(N-[5-(2-fluorophenyl)-1,3,4-thiadiazol-2-yl]-3-({[...)
Affinity DataIC50: 4.40E+4nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2019
Entry Details
US Patent