BDBM300582 N-[5-(3-fluorophenyl)-1,3,4-thiadiazol-2-yl]-3-{[(4-methylpiperazin-1-yl)acetyl]amino}-4-(trifluoromethoxy)benzamide::US10130633, Example 152

SMILES CN1CCN(CC(=O)Nc2cc(ccc2OC(F)(F)F)C(=O)Nc2nnc(s2)-c2cccc(F)c2)CC1

InChI Key InChIKey=AVIAJJJEFUNBGD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 300582   

TargetProtein Wnt-3a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300582(N-[5-(3-fluorophenyl)-1,3,4-thiadiazol-2-yl]-3-{[(...)
Affinity DataIC50: >5.00E+4nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Wnt-3a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300582(N-[5-(3-fluorophenyl)-1,3,4-thiadiazol-2-yl]-3-{[(...)
Affinity DataIC50:  200nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent