BDBM300594 3-({[(3R)-3,4-dimethylpiperazin-1-yl]acetyl}amino)-N-[6-(2-fluorophenyl)pyridin-3-yl]-4-(trifluoromethoxy)benzamide::US10130633, Example 164

SMILES C[C@@H]1CN(CC(=O)Nc2cc(ccc2OC(F)(F)F)C(=O)Nc2ccc(nc2)-c2ccccc2F)CCN1C

InChI Key InChIKey=IBSFTHPGPUBNAB-QGZVFWFLSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 300594   

TargetProtein Wnt-3a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300594(3-({[(3R)-3,4-dimethylpiperazin-1-yl]acetyl}amino)...)
Affinity DataIC50: >5.00E+4nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Wnt-3a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300594(3-({[(3R)-3,4-dimethylpiperazin-1-yl]acetyl}amino)...)
Affinity DataIC50:  220nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent