BDBM300640 N-[6-(2-fluorophenyl)pyridin-3- yl]-3-{[(4-methylpiperazin-1- yl)acetyl]amino}-4- (trifluoromethyl)benzamide::US10130633, Example 210

SMILES CN1CCN(CC(=O)Nc2cc(ccc2C(F)(F)F)C(=O)Nc2ccc(nc2)-c2ccccc2F)CC1

InChI Key InChIKey=LEVIESVMAYMBRU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 300640   

TargetProtein Wnt-3a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300640(N-[6-(2-fluorophenyl)pyridin-3- yl]-3-{[(4-methylp...)
Affinity DataIC50:  2.95E+4nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Wnt-3a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300640(N-[6-(2-fluorophenyl)pyridin-3- yl]-3-{[(4-methylp...)
Affinity DataIC50:  152nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent