BDBM300643 6-(2-fluorophenyl)-N-[3-{[2- (morpholin-4- yl)propanoyl]amino}-4- (trifluoromethoxy)phenyl] nicotinamide::US10130633, Example 213

SMILES CC(N1CCOCC1)C(=O)Nc1cc(NC(=O)c2ccc(nc2)-c2ccccc2F)ccc1OC(F)(F)F

InChI Key InChIKey=XFZOXFOCQJSZKQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 300643   

TargetProtein Wnt-3a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300643(6-(2-fluorophenyl)-N-[3-{[2- (morpholin-4- yl)prop...)
Affinity DataIC50: >5.00E+4nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Wnt-3a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300643(6-(2-fluorophenyl)-N-[3-{[2- (morpholin-4- yl)prop...)
Affinity DataIC50:  140nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent