BDBM300663 N-[6-(2-fluorophenyl)pyridin-3- yl]-3-({[4-(2,2,2- trifluoroethyl)piperazin-1- yl]acetyl}amino)-4- (trifluoromethoxy)benzamide::US10130633, Example 233

SMILES Fc1ccccc1-c1ccc(NC(=O)c2ccc(OC(F)(F)F)c(NC(=O)CN3CCN(CC(F)(F)F)CC3)c2)cn1

InChI Key InChIKey=JXJVCGNQKUAUGB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 300663   

TargetProtein Wnt-3a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300663(N-[6-(2-fluorophenyl)pyridin-3- yl]-3-({[4-(2,2,2-...)
Affinity DataIC50: >5.00E+4nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Wnt-3a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300663(N-[6-(2-fluorophenyl)pyridin-3- yl]-3-({[4-(2,2,2-...)
Affinity DataIC50:  985nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent