BDBM300665 4-[(methylsulfonyl)methyl]-3- [(morpholin-4-ylacetyl)amino]- N-(5-phenyl-1,3,4-thiadiazol-2- yl)benzamide::US10130633, Example 235

SMILES CS(=O)(=O)Cc1ccc(cc1NC(=O)CN1CCOCC1)C(=O)Nc1nnc(s1)-c1ccccc1

InChI Key InChIKey=LWANVTRQRKFEOL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 300665   

TargetProtein Wnt-3a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300665(4-[(methylsulfonyl)methyl]-3- [(morpholin-4-ylacet...)
Affinity DataIC50: >5.00E+4nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Wnt-3a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300665(4-[(methylsulfonyl)methyl]-3- [(morpholin-4-ylacet...)
Affinity DataIC50:  1.31E+3nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent