BDBM300707 (2S,4S)-4-[(5-Chloro-2H-[1,2,4]triazole-3-carbonyl)amino]-5-(3′-fluorobiphenyl-4-yl)-2-hydroxymethyl-pentanoic acid::US10130642, Example 3B

SMILES OC[C@H](C[C@@H](Cc1ccc(cc1)-c1cccc(F)c1)NC(=O)c1nc(Cl)n[nH]1)C(O)=O

InChI Key

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 300707   

TargetNeprilysin(Homo sapiens (Human))
Theravance Biopharma R&D Ip

US Patent
LigandPNGBDBM300707((2S,4S)-4-[(5-Chloro-2H-[1,2,4]triazole-3-carbonyl...)
Affinity DataKi: <1nMAssay Description:Recombinant human NEP and recombinant human ACE were obtained commercially (R&D Systems, Minneapolis, Minn., catalog numbers 1182-ZN and 929-ZN, resp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent