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BDBM30082 triazolothiadiazine, 8A

SMILES: COc1ccc(cc1)C1=Nn2c(SC1)nnc2-c1ccccc1OC

InChI Key: InChIKey=VGMTZVDPDBJASM-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 30082   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A


(Homo sapiens (Human))
BDBM30082
PNG
(triazolothiadiazine, 8A)
Show SMILES COc1ccc(cc1)C1=Nn2c(SC1)nnc2-c1ccccc1OC
Show InChI InChI=1S/C18H16N4O2S/c1-23-13-9-7-12(8-10-13)15-11-25-18-20-19-17(22(18)21-15)14-5-3-4-6-16(14)24-2/h3-10H,11H2,1-2H3
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Similars

Article
PubMed
n/an/a>2.00E+4n/an/an/an/an/an/a



NIH



Assay Description
Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...


Bioorg Med Chem Lett 18: 1297-303 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.028
BindingDB Entry DOI: 10.7270/Q2RB72ZX
More data for this
Ligand-Target Pair