BDBM3010 3-((3-Chlorophenyl)amino)-4-((3-methylphenyl)amino)-1H-pyrazolo[3,4-d]pyrimidine::3-N-(3-chlorophenyl)-4-N-(3-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidine-3,4-diamine::4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 11

SMILES Cc1cccc(Nc2ncnc3n[nH]c(Nc4cccc(Cl)c4)c23)c1

InChI Key InChIKey=PLZVTPONFFMTDM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 3010   

TargetProtein kinase C alpha type(Bos taurus (bovine))
Novartis Pharmaceuticals

LigandPNGBDBM3010(3-((3-Chlorophenyl)amino)-4-((3-methylphenyl)amino...)
Affinity DataIC50:  4.70E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase transforming protein Abl(Abelson murine leukemia virus)
Novartis Pharmaceuticals

LigandPNGBDBM3010(3-((3-Chlorophenyl)amino)-4-((3-methylphenyl)amino...)
Affinity DataIC50:  1.65E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM3010(3-((3-Chlorophenyl)amino)-4-((3-methylphenyl)amino...)
Affinity DataIC50:  130nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM3010(3-((3-Chlorophenyl)amino)-4-((3-methylphenyl)amino...)
Affinity DataIC50:  8.08E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed