BDBM301056 4-{1-[((3R)pyrrolidin-3-yl)methyl]-5- (4-methoxyphenyl)pyrrolo[3,2- b]pyridin-6-yl}benzenecarbonitrile::US10131664, Example 49

SMILES COc1ccc(cc1)-c1nc2ccn(C[C@@H]3CCNC3)c2cc1-c1ccc(cc1)C#N

InChI Key InChIKey=NNGNNKPLMFKJAE-LJQANCHMSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 301056   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM301056(4-{1-[((3R)pyrrolidin-3-yl)methyl]-5- (4-methoxyph...)
Affinity DataIC50: <10nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent