BDBM30133 tetrahydrofuranyl ethylamine, 24

SMILES CNCCC1CCC(CCc2cc(F)ccc2OC)O1

InChI Key InChIKey=NTTIJAHCUAQKMW-UHFFFAOYSA-N

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 30133   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Human Biomolecular Research Institute

LigandPNGBDBM30133(tetrahydrofuranyl ethylamine, 24)
Affinity DataKi:  21.2nM ΔG°:  -10.4kcal/mole EC50:  18.4nMpH: 7.4 T: 2°CAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Human Biomolecular Research Institute

LigandPNGBDBM30133(tetrahydrofuranyl ethylamine, 24)
Affinity DataKi:  1.93E+4nM EC50:  2.04E+4nMAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Human Biomolecular Research Institute

LigandPNGBDBM30133(tetrahydrofuranyl ethylamine, 24)
Affinity DataKi:  6.70E+4nM ΔG°:  -5.63kcal/mole EC50: >1.00E+5nMpH: 7.4 T: 2°CAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed