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BDBM30229 carboline analog, 41

SMILES: CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1ncccn1

InChI Key: InChIKey=KDRXCVVKZIRYMZ-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 30229   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (Human))
BDBM30229
PNG
(carboline analog, 41)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1ncccn1
Show InChI InChI=1/C17H15N5O2/c1-9-8-20-16(24)14-13(9)11-7-10(3-4-12(11)21-14)15(23)22-17-18-5-2-6-19-17/h2-7,9,21H,8H2,1H3,(H,20,24)(H,18,19,22,23)
PDB
MMDB

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Similars

Article
PubMed
n/an/a>2.00E+4n/an/an/an/a7.625



Boehringer Ingelheim Pharmaceuticals Inc



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair