BDBM302495 N5-(4-Cyanophenyl)-2- (3-fluorophenyl)-6,7- dihydropyrazolo[1,5-a] pyrazine-3,5(4H)- dicarboxamide::US9598423, Example 61

SMILES NC(=O)c1c2CN(CCn2nc1-c1cccc(F)c1)C(=O)Nc1ccc(cc1)[N+]#[C-]

InChI Key InChIKey=KHZUJLNGXYSGPN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 302495   

TargetCasein kinase I isoform delta(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM302495(N5-(4-Cyanophenyl)-2- (3-fluorophenyl)-6,7- dihydr...)
Affinity DataIC50: <10nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM302495(N5-(4-Cyanophenyl)-2- (3-fluorophenyl)-6,7- dihydr...)
Affinity DataIC50: <10nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent