BDBM3032 CHEMBL1204168::CHEMBL29197::N-(3-bromophenyl)-6,7-dimethoxyquinazolin-4-amine::PD153035::US11001595, Compound PD153035::US11111252, Compound PD153035::US9422297, PD153035

SMILES: COc1cc2ncnc(Nc3cccc(Br)c3)c2cc1OC

InChI Key: InChIKey=LSPANGZZENHZNJ-UHFFFAOYSA-N

Data: 1 KI  62 IC50  2 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 65 hits for monomerid = 3032   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Human)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor beta (Rat)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.19E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
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MAP kinase-interacting serine/threonine-protein kinase 1 (Human)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
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Fructose-1,6-bisphosphatase 1 (Pig)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Fructose-1,6-bisphosphatase 1 (Rat)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Fructose-1,6-bisphosphatase 1 (Human)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Receptor tyrosine-protein kinase erbB-4 (Human)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.660	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	143	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.49E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.0250	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	70.8	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Broad substrate specificity ATP-binding cassette transporter ABCG2 (Human)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Broad substrate specificity ATP-binding cassette transporter ABCG2 (Human)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.73E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.0290	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.0250	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase transforming protein Abl (Abelson murine leukemia virus)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Protein kinase C alpha type (Bovine)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Human)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.0250	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.0290	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	16	n/a	n/a	n/a	n/a	7.6	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	7.4	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.0950	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<15	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM3032 (CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair