BDBM3033 3-{23-methyl-14-oxo-3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,22}]tricosa-1(16),2(10),4(9),5,7,11(15),17,19,21-nonaen-3-yl}propanenitrile::CHEMBL302449::Go 6976::Indolocarbazole deriv.

SMILES: Cn1c2ccccc2c3c1c4c(c5ccccc5n4CCC#N)c6c3C(=O)NC6

InChI Key: InChIKey=VWVYILCFSYNJHF-UHFFFAOYSA-N

Data: 6 KI  35 IC50  1 EC50

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 42 hits for monomerid = 3033   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-dependent protein kinase 1 (Bovine)	BDBM3033 (Indolocarbazole deriv. | 3-{23-methyl-14-oxo-3,13,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Dual specificity protein kinase TTK (Human)	BDBM3033 (Indolocarbazole deriv. | 3-{23-methyl-14-oxo-3,13,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.99E+3	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM3033 (Indolocarbazole deriv. | 3-{23-methyl-14-oxo-3,13,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.82E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM3033 (Indolocarbazole deriv. | 3-{23-methyl-14-oxo-3,13,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM3033 (Indolocarbazole deriv. | 3-{23-methyl-14-oxo-3,13,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM3033 (Indolocarbazole deriv. | 3-{23-methyl-14-oxo-3,13,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	187	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM3033 (Indolocarbazole deriv. | 3-{23-methyl-14-oxo-3,13,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	163	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM3033 (Indolocarbazole deriv. | 3-{23-methyl-14-oxo-3,13,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Protein kinase C alpha type (Human)	BDBM3033 (Indolocarbazole deriv. | 3-{23-methyl-14-oxo-3,13,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Protein kinase C beta type (Human)	BDBM3033 (Indolocarbazole deriv. | 3-{23-methyl-14-oxo-3,13,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
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Myosin light chain kinase, smooth muscle (Chicken)	BDBM3033 (Indolocarbazole deriv. | 3-{23-methyl-14-oxo-3,13,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rat)	BDBM3033 (Indolocarbazole deriv. | 3-{23-methyl-14-oxo-3,13,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit alpha (Bovine)	BDBM3033 (Indolocarbazole deriv. | 3-{23-methyl-14-oxo-3,13,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Protein kinase C alpha/beta/delta/epsilon/eta/gamma/theta/zeta type (Rat)	BDBM3033 (Indolocarbazole deriv. | 3-{23-methyl-14-oxo-3,13,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D1 (Human)	BDBM3033 (Indolocarbazole deriv. | 3-{23-methyl-14-oxo-3,13,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Human)	BDBM3033 (Indolocarbazole deriv. | 3-{23-methyl-14-oxo-3,13,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D1 (Human)	BDBM3033 (Indolocarbazole deriv. | 3-{23-methyl-14-oxo-3,13,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C delta type (Human)	BDBM3033 (Indolocarbazole deriv. | 3-{23-methyl-14-oxo-3,13,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	446	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Human)	BDBM3033 (Indolocarbazole deriv. | 3-{23-methyl-14-oxo-3,13,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C gamma type (Human)	BDBM3033 (Indolocarbazole deriv. | 3-{23-methyl-14-oxo-3,13,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C beta type (Human)	BDBM3033 (Indolocarbazole deriv. | 3-{23-methyl-14-oxo-3,13,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK2 (Human)	BDBM3033 (Indolocarbazole deriv. | 3-{23-methyl-14-oxo-3,13,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Human)	BDBM3033 (Indolocarbazole deriv. | 3-{23-methyl-14-oxo-3,13,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK3 (Human)	BDBM3033 (Indolocarbazole deriv. | 3-{23-methyl-14-oxo-3,13,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D1 (Human)	BDBM3033 (Indolocarbazole deriv. | 3-{23-methyl-14-oxo-3,13,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM3033 (Indolocarbazole deriv. | 3-{23-methyl-14-oxo-3,13,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Aurora kinase B (Human)	BDBM3033 (Indolocarbazole deriv. | 3-{23-methyl-14-oxo-3,13,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Aurora kinase A (Human)	BDBM3033 (Indolocarbazole deriv. | 3-{23-methyl-14-oxo-3,13,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	118	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM3033 (Indolocarbazole deriv. | 3-{23-methyl-14-oxo-3,13,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Human)	BDBM3033 (Indolocarbazole deriv. | 3-{23-methyl-14-oxo-3,13,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Chicken)	BDBM3033 (Indolocarbazole deriv. | 3-{23-methyl-14-oxo-3,13,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	7.2	30
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					More data for this Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit alpha (Bovine)	BDBM3033 (Indolocarbazole deriv. | 3-{23-methyl-14-oxo-3,13,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
cGMP-dependent protein kinase 1 (Bovine)	BDBM3033 (Indolocarbazole deriv. | 3-{23-methyl-14-oxo-3,13,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Mouse)	BDBM3033 (Indolocarbazole deriv. | 3-{23-methyl-14-oxo-3,13,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Human)	BDBM3033 (Indolocarbazole deriv. | 3-{23-methyl-14-oxo-3,13,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Blk (Mouse)	BDBM3033 (Indolocarbazole deriv. | 3-{23-methyl-14-oxo-3,13,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK4 (Human)	BDBM3033 (Indolocarbazole deriv. | 3-{23-methyl-14-oxo-3,13,...) Show SMILES Show InChI	GoogleScholar	UniChem		3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK4 (Human)	BDBM3033 (Indolocarbazole deriv. | 3-{23-methyl-14-oxo-3,13,...) Show SMILES Show InChI	GoogleScholar	UniChem		3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK4 (Human)	BDBM3033 (Indolocarbazole deriv. | 3-{23-methyl-14-oxo-3,13,...) Show SMILES Show InChI	GoogleScholar	UniChem		3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Human)	BDBM3033 (Indolocarbazole deriv. | 3-{23-methyl-14-oxo-3,13,...) Show SMILES Show InChI	GoogleScholar	UniChem		>8.00E+3	>-6.88	n/a	n/a	n/a	n/a	n/a	7.5	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK3 (Human)	BDBM3033 (Indolocarbazole deriv. | 3-{23-methyl-14-oxo-3,13,...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK2 (Human)	BDBM3033 (Indolocarbazole deriv. | 3-{23-methyl-14-oxo-3,13,...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair