BDBM304692 (S)-2-isopropyl-4-(3-(methylsulfonyl)phenyl)-1-(((3S,6R)-6-(trifluoromethyl)tetrahydro-2H-pyran-3-yl)methyl)piperazine::US10144715, Compound 49-8

SMILES CC(C)[C@H]1CN(CCN1C[C@@H]1CC[C@@H](OC1)C(F)(F)F)c1cccc(c1)S(C)(=O)=O

InChI Key InChIKey=GEXZSCVAMWWQAV-PWIZWCRZSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 304692   

TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM304692((S)-2-isopropyl-4-(3-(methylsulfonyl)phenyl)-1-(((...)
Affinity DataKi:  11nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM304692((S)-2-isopropyl-4-(3-(methylsulfonyl)phenyl)-1-(((...)
Affinity DataKi:  84nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent