BDBM304694 (2S)-2-(4-fluorophenyl)-4-(3-(methylsulfonyl)phenyl)-1-(((3R)-6-(trifluoromethyl)tetrahydro-2H-pyran-3-yl)methyl)piperazine::US10144715, Compound 49-10

SMILES CS(=O)(=O)c1cccc(c1)N1CCN(C[C@H]2CC[C@@H](OC2)C(F)(F)F)[C@H](C1)c1ccc(F)cc1

InChI Key InChIKey=ISUZFVXNJCGBJL-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 304694   

TargetOxysterols receptor LXR-beta(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM304694((2S)-2-(4-fluorophenyl)-4-(3-(methylsulfonyl)pheny...)
Affinity DataKi:  53nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetOxysterols receptor LXR-alpha(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM304694((2S)-2-(4-fluorophenyl)-4-(3-(methylsulfonyl)pheny...)
Affinity DataKi:  438nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent