BDBM3057 2-(butylamino)-6-(2,6-dichlorophenyl)-8-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one::2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 24::PD 166285 analog

SMILES CCCCNc1ncc2cc(-c3c(Cl)cccc3Cl)c(=O)n(C)c2n1

InChI Key InChIKey=QOSLUZXSYUGPOU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 3057   

TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3057(2-(butylamino)-6-(2,6-dichlorophenyl)-8-methyl-7H,...)
Affinity DataIC50:  1.03E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3057(2-(butylamino)-6-(2,6-dichlorophenyl)-8-methyl-7H,...)
Affinity DataIC50:  4.40E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3057(2-(butylamino)-6-(2,6-dichlorophenyl)-8-methyl-7H,...)
Affinity DataIC50:  2.30E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3057(2-(butylamino)-6-(2,6-dichlorophenyl)-8-methyl-7H,...)
Affinity DataIC50:  4.48E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed