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BDBM30590 US8853258, 278

SMILES: CC1=C(COc2ccc(CCC(C)(C(=O)NO)S(C)(=O)=O)cc2)NC(O1)c1cccc(C)c1

InChI Key: InChIKey=BJNFTLNVRZKOSQ-RMLRFSFXSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 30590   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM30590
PNG
(US8853258, 278)
Show SMILES CC1=C(COc2ccc(CCC(C)(C(=O)NO)S(C)(=O)=O)cc2)NC(O1)c1cccc(C)c1
Show InChI InChI=1S/C27H22N4O5/c1-3-35-27(34)21-15-20-23(28-22-17(2)9-7-13-30(22)26(20)33)31(16-19-12-8-14-36-19)24(21)29-25(32)18-10-5-4-6-11-18/h4-15H,3,16H2,1-2H3/b29-24+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 10.4n/an/an/an/a8.0n/a



Pfizer Inc

US Patent


Assay Description
IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...


US Patent US8853258 (2014)


BindingDB Entry DOI: 10.7270/Q25M64DP
More data for this
Ligand-Target Pair