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BDBM30647 MLS-0291694.0001::N-(4-thiazolo[5,4-b]pyridin-2-ylphenyl)ethanesulfonamide::N-[4-(2-thiazolo[5,4-b]pyridinyl)phenyl]ethanesulfonamide::N-[4-([1,3]thiazolo[5,4-b]pyridin-2-yl)phenyl]ethanesulfonamide::cid_16194594

SMILES: CCS(=O)(=O)Nc1ccc(cc1)-c1nc2cccnc2s1

InChI Key: InChIKey=HPLPIUZUPXOANW-UHFFFAOYSA-N

Data: 1 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 30647   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM30647
PNG
(MLS-0291694.0001 | N-(4-thiazolo[5,4-b]pyridin-2-y...)
Show SMILES CCS(=O)(=O)Nc1ccc(cc1)-c1nc2cccnc2s1
Show InChI InChI=1S/C14H13N3O2S2/c1-2-21(18,19)17-11-7-5-10(6-8-11)13-16-12-4-3-9-15-14(12)20-13/h3-9,17H,2H2,1H3
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

n/an/a 1.28E+4n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q25D8Q6Q
More data for this
Ligand-Target Pair
corticotropin releasing factor-binding protein


(Homo sapiens)
BDBM30647
PNG
(MLS-0291694.0001 | N-(4-thiazolo[5,4-b]pyridin-2-y...)
Show SMILES CCS(=O)(=O)Nc1ccc(cc1)-c1nc2cccnc2s1
Show InChI InChI=1S/C14H13N3O2S2/c1-2-21(18,19)17-11-7-5-10(6-8-11)13-16-12-4-3-9-15-14(12)20-13/h3-9,17H,2H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

n/an/an/an/a>5.30E+4n/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2012)


BindingDB Entry DOI: 10.7270/Q2VX0F3D
More data for this
Ligand-Target Pair
Hsf1 protein


(Mus musculus)
BDBM30647
PNG
(MLS-0291694.0001 | N-(4-thiazolo[5,4-b]pyridin-2-y...)
Show SMILES CCS(=O)(=O)Nc1ccc(cc1)-c1nc2cccnc2s1
Show InChI InChI=1S/C14H13N3O2S2/c1-2-21(18,19)17-11-7-5-10(6-8-11)13-16-12-4-3-9-15-14(12)20-13/h3-9,17H,2H2,1H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

n/an/an/an/a 9.29E+4n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2MW2FKX
More data for this
Ligand-Target Pair