BDBM30703 2-(4-tert-butyl-2,6-dimethyl-benzyl)-2-imidazoline;hydrochloride::2-[(4-tert-butyl-2,6-dimethyl-phenyl)methyl]-4,5-dihydro-1H-imidazole;hydrochloride::2-[(4-tert-butyl-2,6-dimethylphenyl)methyl]-4,5-dihydro-1H-imidazole;hydrochloride::CHEMBL312448::MLS000069695::SMR000058526::XYLOMETAZOLINE HYDROCHLORIDE::Xylometazoline::cid_5282386

SMILES: Cc1cc(cc(C)c1CC1=NCCN1)C(C)(C)C

InChI Key: InChIKey=HUCJFAOMUPXHDK-UHFFFAOYSA-N

Data: 13 KI  4 IC50  5 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 22 hits for monomerid = 30703   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Human)	BDBM30703 (SMR000058526 | 2-[(4-tert-butyl-2,6-dimethyl-pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	129	n/a	n/a	7.4	23
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Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (Rat)	BDBM30703 (SMR000058526 | 2-[(4-tert-butyl-2,6-dimethyl-pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rat)	BDBM30703 (SMR000058526 | 2-[(4-tert-butyl-2,6-dimethyl-pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1D (Human)	BDBM30703 (SMR000058526 | 2-[(4-tert-butyl-2,6-dimethyl-pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	369	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM30703 (SMR000058526 | 2-[(4-tert-butyl-2,6-dimethyl-pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>7.96E+5	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Human)	BDBM30703 (SMR000058526 | 2-[(4-tert-butyl-2,6-dimethyl-pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	9.90E+4	n/a	n/a	7.4	23
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5-hydroxytryptamine receptor 1E (Human)	BDBM30703 (SMR000058526 | 2-[(4-tert-butyl-2,6-dimethyl-pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	87	n/a	n/a	7.4	23
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Sphingosine 1-phosphate receptor 3 (Human)	BDBM30703 (SMR000058526 | 2-[(4-tert-butyl-2,6-dimethyl-pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a
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RecBCD enzyme subunit RecD (Escherichia coli (strain K12))	BDBM30703 (SMR000058526 | 2-[(4-tert-butyl-2,6-dimethyl-pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.19E+5	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1D (Human)	BDBM30703 (SMR000058526 | 2-[(4-tert-butyl-2,6-dimethyl-pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1D (Human)	BDBM30703 (SMR000058526 | 2-[(4-tert-butyl-2,6-dimethyl-pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor/Alpha-1B adrenergic receptor/Alpha-1D adrenergic receptor/Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (Rat)	BDBM30703 (SMR000058526 | 2-[(4-tert-butyl-2,6-dimethyl-pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		4.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Rat)	BDBM30703 (SMR000058526 | 2-[(4-tert-butyl-2,6-dimethyl-pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		4.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1B (Human)	BDBM30703 (SMR000058526 | 2-[(4-tert-butyl-2,6-dimethyl-pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1B (Human)	BDBM30703 (SMR000058526 | 2-[(4-tert-butyl-2,6-dimethyl-pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2A adrenergic receptor (Human)	BDBM30703 (SMR000058526 | 2-[(4-tert-butyl-2,6-dimethyl-pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		15.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2A adrenergic receptor (Mouse)	BDBM30703 (SMR000058526 | 2-[(4-tert-butyl-2,6-dimethyl-pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		24.0	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2A adrenergic receptor (Mouse)	BDBM30703 (SMR000058526 | 2-[(4-tert-butyl-2,6-dimethyl-pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		25.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Rat)	BDBM30703 (SMR000058526 | 2-[(4-tert-butyl-2,6-dimethyl-pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Human)	BDBM30703 (SMR000058526 | 2-[(4-tert-butyl-2,6-dimethyl-pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2C adrenergic receptor (Human)	BDBM30703 (SMR000058526 | 2-[(4-tert-butyl-2,6-dimethyl-pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		129	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2B adrenergic receptor (Human)	BDBM30703 (SMR000058526 | 2-[(4-tert-butyl-2,6-dimethyl-pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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