BDBM30705 CHEMBL744::MLS000069369::RILUZOLE::SMR000058231::cid_5070

SMILES: c1cc2c(cc1OC(F)(F)F)sc(n2)N

InChI Key: InChIKey=FTALBRSUTCGOEG-UHFFFAOYSA-N

Data: 1 KI  22 IC50  2 EC50

PDB links: 6 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 26 hits for monomerid = 30705   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 4 subunit alpha (Human)	BDBM30705 (SMR000058231 | CHEMBL744 | cid_5070 | MLS000069369...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium channel subfamily K member 2 (Human)	BDBM30705 (SMR000058231 | CHEMBL744 | cid_5070 | MLS000069369...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.39E+5	n/a	n/a	n/a	n/a
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UDP-glucuronosyltransferase 1A1 (Human)	BDBM30705 (SMR000058231 | CHEMBL744 | cid_5070 | MLS000069369...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80E+5	n/a	n/a	n/a	n/a	n/a	n/a
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UDP-glucuronosyltransferase 1A1 (Human)	BDBM30705 (SMR000058231 | CHEMBL744 | cid_5070 | MLS000069369...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydrofolate reductase (Human)	BDBM30705 (SMR000058231 | CHEMBL744 | cid_5070 | MLS000069369...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.12E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Pteridine reductase 1 (Leishmania major)	BDBM30705 (SMR000058231 | CHEMBL744 | cid_5070 | MLS000069369...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 2 subunit alpha (Rat)	BDBM30705 (SMR000058231 | CHEMBL744 | cid_5070 | MLS000069369...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.73E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 2 subunit alpha (Human)	BDBM30705 (SMR000058231 | CHEMBL744 | cid_5070 | MLS000069369...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Ryanodine receptor 2 (Mouse)	BDBM30705 (SMR000058231 | CHEMBL744 | cid_5070 | MLS000069369...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	9.90E+3	n/a	n/a	n/a	n/a
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Sodium channel protein type 9 subunit alpha (Human)	BDBM30705 (SMR000058231 | CHEMBL744 | cid_5070 | MLS000069369...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 4 subunit alpha (Human)	BDBM30705 (SMR000058231 | CHEMBL744 | cid_5070 | MLS000069369...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 9 subunit alpha (Human)	BDBM30705 (SMR000058231 | CHEMBL744 | cid_5070 | MLS000069369...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Human)	BDBM30705 (SMR000058231 | CHEMBL744 | cid_5070 | MLS000069369...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	9.90E+4	n/a	n/a	7.4	23
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Cytochrome P450 2C19 (Human)	BDBM30705 (SMR000058231 | CHEMBL744 | cid_5070 | MLS000069369...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM30705 (SMR000058231 | CHEMBL744 | cid_5070 | MLS000069369...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM30705 (SMR000058231 | CHEMBL744 | cid_5070 | MLS000069369...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Pteridine reductase 1 (Leishmania major)	BDBM30705 (SMR000058231 | CHEMBL744 | cid_5070 | MLS000069369...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.41E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM30705 (SMR000058231 | CHEMBL744 | cid_5070 | MLS000069369...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM30705 (SMR000058231 | CHEMBL744 | cid_5070 | MLS000069369...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM30705 (SMR000058231 | CHEMBL744 | cid_5070 | MLS000069369...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 4 (Human)	BDBM30705 (SMR000058231 | CHEMBL744 | cid_5070 | MLS000069369...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM30705 (SMR000058231 | CHEMBL744 | cid_5070 | MLS000069369...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 2 (Human)	BDBM30705 (SMR000058231 | CHEMBL744 | cid_5070 | MLS000069369...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 3 (Human)	BDBM30705 (SMR000058231 | CHEMBL744 | cid_5070 | MLS000069369...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM30705 (SMR000058231 | CHEMBL744 | cid_5070 | MLS000069369...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.39E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Pteridine reductase 1 (Leishmania major)	BDBM30705 (SMR000058231 | CHEMBL744 | cid_5070 | MLS000069369...) Show SMILES Show InChI	GoogleScholar	UniChem		4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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