BDBM307836 (3R)-N-(5-chloro-4-{1-[(4-cyanotetrahydro-2H-pyran-4-yl)methyl]-1H-yl}pyridin-2-yl)piperidine-3-carboxamide::US9650358, Example 132

SMILES NC(=O)[C@@H]1CCCN(C1)c1cc(CC2(CCOCC2)C#N)c(Cl)cn1

InChI Key InChIKey=DUGXOEBOVYAAPJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 307836   

TargetCyclin-dependent kinase 9(Human)
Abbvie

US Patent
LigandPNGBDBM307836(US9650358, Example 132 | (3R)-N-(5-chloro-4-{1-[(4...)
Affinity DataIC50: 130nMAssay Description:CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
US Patent