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BDBM308373 US9649309, Compound UNC1819A

SMILES: CCCCNc1ncc(C(=O)Nc2ccc(F)cc2)c(NC2CC[C@H](O)CC2)n1

InChI Key: InChIKey=DLNOLRVJSOGNNN-SKHKEOPYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 308373   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM308373
PNG
(US9649309, Compound UNC1819A)
Show SMILES CCCCNc1ncc(C(=O)Nc2ccc(F)cc2)c(NC2CC[C@H](O)CC2)n1
Show InChI InChI=1S/C21H28FN5O2/c1-2-3-12-23-21-24-13-18(20(29)26-16-6-4-14(22)5-7-16)19(27-21)25-15-8-10-17(28)11-9-15/h4-7,13,15,17,28H,2-3,8-12H2,1H3,(H,26,29)(H2,23,24,25,27)/t15?,17-
PDB
MMDB

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KEGG

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PC cid
PC sid
UniChem
US Patent
n/an/a 55n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)


BindingDB Entry DOI: 10.7270/Q26Q209H
More data for this
Ligand-Target Pair