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BDBM308499 3-fluoro-N-{trans-1-[(1-methyl-1H-imidazol-4-yl)sulfonyl]-4-phenylpyrrolidin-3-yl}benzamide::US9656955, Example 18

SMILES: Cn1cnc(c1)S(=O)(=O)N1C[C@@H](NC(=O)c2cccc(F)c2)[C@@H](C1)c1ccccc1

InChI Key: InChIKey=CNPPGHHHDFTPND-RBUKOAKNSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 308499   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM308499
PNG
(3-fluoro-N-{trans-1-[(1-methyl-1H-imidazol-4-yl)su...)
Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@@H](NC(=O)c2cccc(F)c2)[C@@H](C1)c1ccccc1
Show InChI InChI=1S/C21H21FN4O3S/c1-25-13-20(23-14-25)30(28,29)26-11-18(15-6-3-2-4-7-15)19(12-26)24-21(27)16-8-5-9-17(22)10-16/h2-10,13-14,18-19H,11-12H2,1H3,(H,24,27)/t18-,19+/m0/s1
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
<1.00E+4n/an/an/an/an/an/an/an/a



AbbVie Inc

US Patent


Assay Description
Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...


US Patent US9656955 (2017)


BindingDB Entry DOI: 10.7270/Q2Z60R48
More data for this
Ligand-Target Pair