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BDBM308952 (3R,4S)-N-[3-(3-chlorophenyl)propyl]-1-[(1-methyl-1H-imidazol-4-yl)sulfonyl]-4-phenylpyrrolidin-3-amine::US9656955, Example 471

SMILES: Cn1cnc(c1)S(=O)(=O)N1C[C@H](NCCCc2cccc(Cl)c2)[C@H](C1)c1ccccc1

InChI Key: InChIKey=VIGUADUCZSISOL-YADHBBJMSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 308952   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM308952
PNG
((3R,4S)-N-[3-(3-chlorophenyl)propyl]-1-[(1-methyl-...)
Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@H](NCCCc2cccc(Cl)c2)[C@H](C1)c1ccccc1
Show InChI InChI=1S/C23H27ClN4O2S/c1-27-16-23(26-17-27)31(29,30)28-14-21(19-9-3-2-4-10-19)22(15-28)25-12-6-8-18-7-5-11-20(24)13-18/h2-5,7,9-11,13,16-17,21-22,25H,6,8,12,14-15H2,1H3/t21-,22+/m1/s1
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UniProtKB/SwissProt

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PC cid
PC sid
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Article
US Patent
<100n/an/an/an/an/an/an/an/a



AbbVie Inc

US Patent


Assay Description
Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...


US Patent US9656955 (2017)


Article DOI: 10.1021/jm050458h
BindingDB Entry DOI: 10.7270/Q2Z60R48
More data for this
Ligand-Target Pair