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BDBM309056 (3S,4R)-N-(3-ethoxypropyl)-4-(4-fluorophenyl)-1-[(1-methyl-1H-imidazol-4-yl)sulfonyl]pyrrolidine-3-carboxamide::US9656955, Example 578

SMILES: CCOCCCNC(=O)[C@@H]1CN(C[C@H]1c1ccc(F)cc1)S(=O)(=O)c1cn(C)cn1

InChI Key: InChIKey=QJGXLHYMHBQTNB-ZWKOTPCHSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 309056   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM309056
PNG
((3S,4R)-N-(3-ethoxypropyl)-4-(4-fluorophenyl)-1-[(...)
Show SMILES CCOCCCNC(=O)[C@@H]1CN(C[C@H]1c1ccc(F)cc1)S(=O)(=O)c1cn(C)cn1
Show InChI InChI=1S/C20H27FN4O4S/c1-3-29-10-4-9-22-20(26)18-12-25(30(27,28)19-13-24(2)14-23-19)11-17(18)15-5-7-16(21)8-6-15/h5-8,13-14,17-18H,3-4,9-12H2,1-2H3,(H,22,26)/t17-,18+/m0/s1
PDB
MMDB

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KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
<1.00E+4n/an/an/an/an/an/an/an/a



AbbVie Inc

US Patent


Assay Description
Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...


US Patent US9656955 (2017)


Article DOI: 10.1021/jm050458h
BindingDB Entry DOI: 10.7270/Q2Z60R48
More data for this
Ligand-Target Pair