BDBM309353 (S)-N-(6-(4-(4-fluorophenoxy)phenyl)pyridin-2-yl)-3-(1H-imidazol-4-yl)-2-(methylsulfonamido)propanamide::US9656959, Example 38

SMILES CS(=O)(=O)N[C@@H](Cc1c[nH]cn1)C(=O)Nc1cccc(n1)-c1ccc(Oc2ccc(F)cc2)cc1

InChI Key

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 309353   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM309353((S)-N-(6-(4-(4-fluorophenoxy)phenyl)pyridin-2-yl)-...)
Affinity DataKi:  19nMAssay Description:In the alternative, the voltage clamp protocol to examine hNav1.7 currents was as follows. First, the standard current-voltage relationship was teste...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM309353((S)-N-(6-(4-(4-fluorophenoxy)phenyl)pyridin-2-yl)-...)
Affinity DataIC50:  140nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent