BDBM309373 (S)-2-Amino-N-{6-[4-(4-fluoro-phenoxy)-phenyl]-pridin-2-yl}-3-hydroxy-propionamide::US9656959, Example 70

SMILES N[C@@H](CO)C(=O)Nc1cccc(n1)-c1ccc(Oc2ccc(F)cc2)cc1

InChI Key InChIKey=MOOAUOBWHFWHIE-KRWDZBQOSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 309373   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM309373((S)-2-Amino-N-{6-[4-(4-fluoro-phenoxy)-phenyl]-pri...)
Affinity DataKi:  46nMAssay Description:In the alternative, the voltage clamp protocol to examine hNav1.7 currents was as follows. First, the standard current-voltage relationship was teste...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM309373((S)-2-Amino-N-{6-[4-(4-fluoro-phenoxy)-phenyl]-pri...)
Affinity DataIC50:  270nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent