BDBM310312 (1R,2S)-1-(5-chloropyrimidin-2-yl)-N-(4-(2,6-dimethoxyphenyl)-5-((S)-5,5-dimethyltetrahydrofuran-2-yl)-4H-1,2,4-triazol-3-yl)-1-methoxypropane-2-sulfonamide or (1R,2S)-1-(5-chloropyrimidin-2-yl)-N-(4-(2,6-dimethoxyphenyl)-5-((R)-5,5-dimethyltetrahydrofuran-2-yl)-4H-1,2,4-triazol-3-yl)-1-methoxypropane-2-sulfonamide::US10150760, Example 108.0::US10150760, Example 109.0

SMILES CO[C@@H]([C@H](C)S(=O)(=O)Nc1nnc([C@H]2CCC(C)(C)O2)n1-c1c(OC)cccc1OC)c1ncc(Cl)cn1

InChI Key InChIKey=LHGZLRGDXLEUQO-QMIHWGKISA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 310312   

TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM310312((1R,2S)-1-(5-chloropyrimidin-2-yl)-N-(4-(2,6-dimet...)
Affinity DataEC50:  0.160nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV-3 expression vector (Sig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM310312((1R,2S)-1-(5-chloropyrimidin-2-yl)-N-(4-(2,6-dimet...)
Affinity DataEC50:  25nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV-3 expression vector (Sig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent