BDBM310348 (S)-2-(4-chlorophenyl)-N-(4-(2,6-dimethoxyphenyl)-5-(tetrahydrofuran-2-yl)-4H-1,2,4-triazol-3-yl)ethanesulfonamide or (R)-2-(4-chlorophenyl)-N-(4-(2,6-dimethoxyphenyl)-5-(tetrahydrofuran-2-yl)-4H-1,2,4-triazol-3-yl)ethanesulfonamide::US10150760, Example 144.0::US10150760, Example 145.0

SMILES COc1cccc(OC)c1-n1c(NS(=O)(=O)CCc2ccc(Cl)cc2)nnc1[C@H]1CCCO1

InChI Key InChIKey=ZEQABYDIPAIJNB-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 310348   

TargetApelin receptor(Human)
Amgen

US Patent
LigandPNGBDBM310348(US10150760, Example 144.0 | US10150760, Example 14...)
Affinity DataEC50:  80nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV-3 expression vector (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetApelin receptor(Human)
Amgen

US Patent
LigandPNGBDBM310348(US10150760, Example 144.0 | US10150760, Example 14...)
Affinity DataEC50:  830nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV-3 expression vector (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent