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BDBM310729 7-((5-Fluoropyridin-2-yl)(3-methyl-1,2,4-thiadiazol-5-yl)amino)-N-hydroxyheptanamide::US10150763, Example CC

SMILES: Cc1nsc(n1)N(CCCCCCC(=O)NO)c1ccc(F)cn1

InChI Key: InChIKey=RUGSZKOQAROHTP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 310729   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histone deacetylase 6


(Homo sapiens (Human))
BDBM310729
PNG
(7-((5-Fluoropyridin-2-yl)(3-methyl-1,2,4-thiadiazo...)
Show SMILES Cc1nsc(n1)N(CCCCCCC(=O)NO)c1ccc(F)cn1
Show InChI InChI=1S/C15H20FN5O2S/c1-11-18-15(24-20-11)21(13-8-7-12(16)10-17-13)9-5-3-2-4-6-14(22)19-23/h7-8,10,23H,2-6,9H2,1H3,(H,19,22)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<500n/an/an/an/an/an/a



Karus Therapeutics Limited

US Patent


Assay Description
The assay is described in WO2008/062201.


US Patent US10150763 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CC1
More data for this
Ligand-Target Pair
Histone deacetylase 1


(Homo sapiens (Human))
BDBM310729
PNG
(7-((5-Fluoropyridin-2-yl)(3-methyl-1,2,4-thiadiazo...)
Show SMILES Cc1nsc(n1)N(CCCCCCC(=O)NO)c1ccc(F)cn1
Show InChI InChI=1S/C15H20FN5O2S/c1-11-18-15(24-20-11)21(13-8-7-12(16)10-17-13)9-5-3-2-4-6-14(22)19-23/h7-8,10,23H,2-6,9H2,1H3,(H,19,22)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 750n/an/an/an/an/an/a



Karus Therapeutics Limited

US Patent


Assay Description
The assay is described in WO2008/062201.


US Patent US10150763 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CC1
More data for this
Ligand-Target Pair