BDBM21079 1-[4-(3-amino-1H-indazol-4-yl)phenyl]-3-(2-fluoro-5-methyl-phenyl)urea::1-[4-(3-amino-1H-indazol-4-yl)phenyl]-3-(2-fluoro-5-methylphenyl)urea::1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluoranyl-5-methyl-phenyl)urea::3-[4-(3-amino-1H-indazol-4-yl)phenyl]-1-(2-fluoro-5-methylphenyl)urea::ABT-869::Aminoindazole, 3::CHEMBL223360::cid_11485656

SMILES: Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)-c2cccc3[nH]nc(N)c23)c1

InChI Key: InChIKey=MPVGZUGXCQEXTM-UHFFFAOYSA-N

Data: 5 KI  60 IC50  823 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 891 hits for monomerid = 21079   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	7.5	22
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Mast/stem cell growth factor receptor Kit (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
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Aromatase (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 1 (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
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Macrophage colony-stimulating factor 1 receptor (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor beta (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
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Angiopoietin-1 receptor (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ABL1 [T315I] (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	7.4	25
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ALK tyrosine kinase receptor (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.60E+3	n/a	n/a	n/a	7.4	25
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Aurora kinase A (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.60E+3	n/a	n/a	n/a	7.4	25
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Aurora kinase B (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a
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Aurora kinase C (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	71	n/a	n/a	n/a	7.4	25
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Tyrosine-protein kinase receptor UFO (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a
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Bone morphogenetic protein receptor type-2 (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	7.80E+3	n/a	n/a	n/a	7.4	25
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Cyclin-dependent kinase 11B (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	7.4	25
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Cyclin-dependent kinase 11A (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	7.4	25
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Cyclin-dependent kinase 19 (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	74	n/a	n/a	n/a	7.4	25
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Cyclin-dependent kinase 7 (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.90E+3	n/a	n/a	n/a	7.4	23
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Cyclin-dependent kinase 8 (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	95	n/a	n/a	n/a	7.4	23
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Cyclin-dependent kinase 9 (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	7.4	23
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Dual specificity protein kinase CLK1 [R432A] (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	8.90E+3	n/a	n/a	n/a	7.4	23
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Dual specificity protein kinase CLK4 (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.60E+3	n/a	n/a	n/a	7.4	23
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Macrophage colony-stimulating factor 1 receptor (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.40	n/a	n/a	n/a	7.4	25
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Epithelial discoidin domain-containing receptor 1 (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	58	n/a	n/a	n/a	7.4	25
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Discoidin domain-containing receptor 2 [A642S] (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.80E+3	n/a	n/a	n/a	7.4	25
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Epidermal growth factor receptor [G719C] (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	6.50E+3	n/a	n/a	n/a	7.4	25
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Ephrin type-A receptor 3 [1-975] (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.50E+3	n/a	n/a	n/a	7.4	25
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Ephrin type-A receptor 7 (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	330	n/a	n/a	n/a	7.4	25
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Ephrin type-A receptor 7 (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	110	n/a	n/a	n/a	7.4	25
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Ephrin type-B receptor 3 (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.40E+3	n/a	n/a	n/a	7.4	25
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Ephrin type-B receptor 4 (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.40E+3	n/a	n/a	n/a	7.4	25
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Mitogen-activated protein kinase 15 (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.80E+3	n/a	n/a	n/a	7.4	25
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Vascular endothelial growth factor receptor 1 (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	7.5	n/a	n/a	n/a	7.4	25
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Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.630	n/a	n/a	n/a	7.4	25
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Receptor-type tyrosine-protein kinase FLT3 [D835H] (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.70	n/a	n/a	n/a	7.4	25
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Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	11	n/a	n/a	n/a	7.4	25
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Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	8.80	n/a	n/a	n/a	7.4	25
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Receptor-type tyrosine-protein kinase FLT3 [N841I] (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.60	n/a	n/a	n/a	7.4	25
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Vascular endothelial growth factor receptor 3 (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	16	n/a	n/a	n/a	7.4	25
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Tyrosine-protein kinase FRK (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	400	n/a	n/a	n/a	7.4	25
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P2Y purinoceptor 14 (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.90E+3	n/a	n/a	n/a	7.4	25
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Mitogen-activated protein kinase 9 (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	240	n/a	n/a	n/a	7.4	25
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Mitogen-activated protein kinase kinase kinase kinase 1 (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	830	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase kinase kinase kinase 3 (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase kinase kinase kinase 5 (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	910	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Mer (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	870	n/a	n/a	n/a	n/a	n/a
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Hepatocyte growth factor receptor (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a
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MAP kinase-interacting serine/threonine-protein kinase 1 (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a
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MAP kinase-interacting serine/threonine-protein kinase 2 (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase 4 (Human)	BDBM21079 (1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a
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