BindingDB PrimarySearch

BDBM31094 PKC-412::cid_24202429

SMILES: [H][C@@]12C[C@@H]([C@H](OC)[C@@](C)(O1)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)c1ccccc1

InChI Key:

Data: 13 KI 2 IC50 156 Kd

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 171 hits for monomerid = 31094
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Tyrosine-protein kinase ABL1 [T315I] (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	3.20E+3	n/a	n/a	n/a	7.4	25
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ALK tyrosine kinase receptor (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	270	n/a	n/a	n/a	7.4	25
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Aurora kinase A (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	120	n/a	n/a	n/a	7.4	25
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Aurora kinase B (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a
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Aurora kinase C (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	170	n/a	n/a	n/a	7.4	25
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Tyrosine-protein kinase receptor UFO (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 19 (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	7.20E+3	n/a	n/a	n/a	7.4	25
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Dual specificity protein kinase CLK1 [R432A] (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	350	n/a	n/a	n/a	7.4	23
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Dual specificity protein kinase CLK4 (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	410	n/a	n/a	n/a	7.4	23
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Macrophage colony-stimulating factor 1 receptor (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	330	n/a	n/a	n/a	7.4	25
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Epithelial discoidin domain-containing receptor 1 (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	7.20E+3	n/a	n/a	n/a	7.4	25
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Epidermal growth factor receptor [G719C] (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	1.50E+3	n/a	n/a	n/a	7.4	25
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Vascular endothelial growth factor receptor 1 (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	450	n/a	n/a	n/a	7.4	25
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Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	11	n/a	n/a	n/a	7.4	25
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Receptor-type tyrosine-protein kinase FLT3 [D835H] (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	6.80	n/a	n/a	n/a	7.4	25
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Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	15	n/a	n/a	n/a	7.4	25
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Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	11	n/a	n/a	n/a	7.4	25
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Receptor-type tyrosine-protein kinase FLT3 [N841I] (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	6	n/a	n/a	n/a	7.4	25
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Vascular endothelial growth factor receptor 3 (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	670	n/a	n/a	n/a	7.4	25
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Tyrosine-protein kinase FRK (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	2.40E+3	n/a	n/a	n/a	7.4	25
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Mitogen-activated protein kinase kinase kinase kinase 1 (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase kinase kinase kinase 3 (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase kinase kinase kinase 5 (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Mer (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a
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Hepatocyte growth factor receptor (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	690	n/a	n/a	n/a	n/a	n/a
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MAP kinase-interacting serine/threonine-protein kinase 2 (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	950	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase 4 (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase 3 (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor alpha (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor beta (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a
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cAMP-dependent protein kinase catalytic subunit alpha (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	720	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase receptor Ret [1-999,M918T] (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase receptor Ret [1-999,M918T] (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a
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Ribosomal protein S6 kinase alpha-4 (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a
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Ribosomal protein S6 kinase alpha-5 (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a
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STE20-like serine/threonine-protein kinase (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase receptor Tie-1 (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a
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Angiopoietin-1 receptor (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a
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High affinity nerve growth factor receptor (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a
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BDNF/NT-3 growth factors receptor (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a
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NT-3 growth factor receptor (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Blk (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a
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Fibroblast growth factor receptor 1 (Human)	BDBM31094 (PKC-412 \| cid_24202429) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a
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