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BDBM31096 CHEMBL290084::Staurosporine::US20240300958, Compound Staurosporine::cid_451705

SMILES: CN[C@H]1C[C@@H]2O[C@](C)([C@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13

InChI Key: InChIKey=HKSZLNNOFSGOKW-UHFFFAOYSA-N

Data: 18 KI 3 IC50 265 Kd

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 286 hits for monomerid = 31096
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Tyrosine-protein kinase Blk (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	25
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Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	0.280	n/a	n/a	n/a	n/a	n/a	25
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Tyrosine-protein kinase ABL1 [T315I] (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	27	n/a	n/a	n/a	7.4	25
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ALK tyrosine kinase receptor (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	32	n/a	n/a	n/a	7.4	25
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Aurora kinase A (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	110	n/a	n/a	n/a	7.4	25
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Aurora kinase B (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a
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Aurora kinase C (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	23	n/a	n/a	n/a	7.4	25
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Tyrosine-protein kinase receptor UFO (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	6.80	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 19 (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	190	n/a	n/a	n/a	7.4	25
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Cyclin-dependent kinase 7 (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	45	n/a	n/a	n/a	7.4	23
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Cyclin-dependent kinase 8 (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	510	n/a	n/a	n/a	7.4	23
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Cyclin-dependent kinase 9 (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	100	n/a	n/a	n/a	7.4	23
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Dual specificity protein kinase CLK1 [R432A] (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	32	n/a	n/a	n/a	7.4	23
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Dual specificity protein kinase CLK4 (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	9.60	n/a	n/a	n/a	7.4	23
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Macrophage colony-stimulating factor 1 receptor (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	12	n/a	n/a	n/a	7.4	25
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Epithelial discoidin domain-containing receptor 1 (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	19	n/a	n/a	n/a	7.4	25
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Discoidin domain-containing receptor 2 [A642S] (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	42	n/a	n/a	n/a	7.4	25
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Epidermal growth factor receptor [G719C] (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	7.4	25
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Ephrin type-A receptor 3 [1-975] (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	27	n/a	n/a	n/a	7.4	25
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Ephrin type-A receptor 7 (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	290	n/a	n/a	n/a	7.4	25
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Ephrin type-A receptor 7 (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	630	n/a	n/a	n/a	7.4	25
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Mitogen-activated protein kinase 15 (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	35	n/a	n/a	n/a	7.4	25
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Vascular endothelial growth factor receptor 1 (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	150	n/a	n/a	n/a	7.4	25
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Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	2.90	n/a	n/a	n/a	7.4	25
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Receptor-type tyrosine-protein kinase FLT3 [D835H] (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	2.10	n/a	n/a	n/a	7.4	25
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Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	2.5	n/a	n/a	n/a	7.4	25
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Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	2.40	n/a	n/a	n/a	7.4	25
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Receptor-type tyrosine-protein kinase FLT3 [N841I] (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	2.10	n/a	n/a	n/a	7.4	25
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Vascular endothelial growth factor receptor 3 (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	28	n/a	n/a	n/a	7.4	25
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Tyrosine-protein kinase FRK (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	45	n/a	n/a	n/a	7.4	25
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P2Y purinoceptor 14 (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	81	n/a	n/a	n/a	7.4	25
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Mitogen-activated protein kinase kinase kinase kinase 1 (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase kinase kinase kinase 3 (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	8.20	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase kinase kinase kinase 5 (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Mer (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	6.40	n/a	n/a	n/a	n/a	n/a
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Hepatocyte growth factor receptor (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a
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MAP kinase-interacting serine/threonine-protein kinase 1 (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a
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MAP kinase-interacting serine/threonine-protein kinase 2 (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase 4 (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	0.190	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase 3 (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	0.180	n/a	n/a	n/a	n/a	n/a
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Muscle, skeletal receptor tyrosine-protein kinase (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	86	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor alpha (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor beta (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a
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cAMP-dependent protein kinase catalytic subunit alpha (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase PLK3 (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	910	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase receptor Ret [1-999,M918T] (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase receptor Ret [1-999,M918T] (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a
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Ribosomal protein S6 kinase alpha-4 (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a
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Ribosomal protein S6 kinase alpha-5 (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a
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STE20-like serine/threonine-protein kinase (Human)	BDBM31096 (CHEMBL290084 \| Staurosporine \| cid_451705 \| US2024...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	0.0200	n/a	n/a	n/a	n/a	n/a
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