BindingDB PrimarySearch

BDBM31099 2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S)-3-hydroxy-1-methyl-4-piperidinyl]-1-benzopyran-4-one::2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S)-3-hydroxy-1-methyl-4-piperidyl]chromone::2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S)-3-hydroxy-1-methylpiperidin-4-yl]chromen-4-one::2-(2-chlorophenyl)-8-[(3S)-1-methyl-3-oxidanyl-piperidin-4-yl]-5,7-bis(oxidanyl)chromen-4-one::CHEMBL45741::Flavopiridol::cid_24867231

SMILES: CN1CCC([C@H](O)C1)c1c(O)cc(O)c2c1oc(cc2=O)-c1ccccc1Cl

InChI Key: InChIKey=BIIVYFLTOXDAOV-UHFFFAOYSA-N

Data: 5 KI 73 Kd

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 78 hits for monomerid = 31099
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Epidermal growth factor receptor (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a
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Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a
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Glycogen synthase kinase-3 beta (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a
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Glycogen synthase kinase-3 alpha (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 7 (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a
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Dual specificity tyrosine-phosphorylation-regulated kinase 1B (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase DCLK3 (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase DCLK1 (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase MRCK beta (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase MRCK alpha (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	9.50E+3	n/a	n/a	n/a	n/a	n/a
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NUAK family SNF1-like kinase 2 (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a
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TGF-beta receptor type-2 (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Srms (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a
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Interferon-induced, double-stranded RNA-activated protein kinase (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase D3 (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase D2 (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase D1 (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a
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ALK tyrosine kinase receptor (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	670	n/a	n/a	n/a	7.4	25
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Cyclin-dependent kinase 14 (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a
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Myotonin-protein kinase (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a
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Protein kinase C epsilon type (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase pim-3 (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase pim-2 (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	770	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase pim-1 (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase kinase kinase 10 (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a
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Calcium/calmodulin-dependent protein kinase type II subunit alpha (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a
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Protein kinase C delta type (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	590	n/a	n/a	n/a	n/a	n/a
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Dual specificity protein kinase CLK3 (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a
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Protein kinase C theta type (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a
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Activin receptor type-2B (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a
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Activin receptor type-1 (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase N1 (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a
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Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase kinase kinase 9 (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a	n/a
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Inhibitor of nuclear factor kappa-B kinase subunit epsilon (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase 17B (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a
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AP2-associated protein kinase 1 (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 15 (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	330	n/a	n/a	n/a	7.4	25
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Cyclin-dependent kinase 18 [3-474] (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a
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MAP kinase-interacting serine/threonine-protein kinase 2 (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Mer (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase kinase kinase kinase 3 (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase kinase kinase kinase 1 (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a
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Receptor-type tyrosine-protein kinase FLT3 [N841I] (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	6.50E+3	n/a	n/a	n/a	7.4	25
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Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	4.60E+3	n/a	n/a	n/a	7.4	25
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Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	3.20E+3	n/a	n/a	n/a	7.4	25
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Receptor-type tyrosine-protein kinase FLT3 [D835H] (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	5.00E+3	n/a	n/a	n/a	7.4	25
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Serine/threonine-protein kinase 3 (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	9.40E+3	n/a	n/a	n/a	n/a	n/a
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Ephrin type-A receptor 3 [1-975] (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	3.30E+3	n/a	n/a	n/a	7.4	25
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Macrophage colony-stimulating factor 1 receptor (Human)	BDBM31099 (CHEMBL45741 \| Flavopiridol \| cid_24867231 \| 2-(2-c...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	2.80E+3	n/a	n/a	n/a	7.4	25
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