BDBM311039 US10155727, Example 11::USRE49517, Example 11

SMILES CCC(CC)n1ccc(Cn2cc(cn2)-c2ccc(Cl)c(OC(F)F)c2)n1

InChI Key InChIKey=VCIYUUWUQVIFEO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 311039   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Janssen Pharmaceuticals

US Patent
LigandPNGBDBM311039(US10155727, Example 11 | USRE49517, Example 11)
Affinity DataIC50:  1.27E+4nMAssay Description:Binding was terminated by filtration of the incubated membrane preparations using Filtermat B (Pharmacia, Uppsala Sweden) and a Micro Cell Harvester ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Janssen Pharmaceuticals

US Patent
LigandPNGBDBM311039(US10155727, Example 11 | USRE49517, Example 11)
Affinity DataIC50: >1.00E+3nMAssay Description:After thawing on the day of the assay, the membrane suspension was diluted further with 20 mM HEPES/0.1 mM KCl/pH 7.2.The incubation mixture of 200 &...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent