BDBM311267 (S)-1-((2′,6-bis(difluoromethyl)-[2,4′-bipyridin]-5-yl)oxy)-2,4-dimethylpentan-2-amine::US10155760, Example 123::US10351563, Example 123::US10544120, Example 123::US10723734, Example 123::US10981910, Example 123::US9902722, Example 123

SMILES: CC(C)C[C@](C)(N)COc1ccc(nc1C(F)F)-c1ccnc(c1)C(F)F

InChI Key: InChIKey=RKAHOQATMSONTM-UHFFFAOYSA-N

Data: 37 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 38 hits for monomerid = 311267   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-G-associated kinase (Human)	BDBM311267 (US10155760, Example 123 | (S)-1-((2′,6-bis(d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
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Solute carrier organic anion transporter family member 1B3 (Human)	BDBM311267 (US10155760, Example 123 | (S)-1-((2′,6-bis(d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium/bile acid cotransporter (Human)	BDBM311267 (US10155760, Example 123 | (S)-1-((2′,6-bis(d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM311267 (US10155760, Example 123 | (S)-1-((2′,6-bis(d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 2 (Human)	BDBM311267 (US10155760, Example 123 | (S)-1-((2′,6-bis(d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Solute carrier family 22 member 6 (Human)	BDBM311267 (US10155760, Example 123 | (S)-1-((2′,6-bis(d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Solute carrier family 22 member 8 (Human)	BDBM311267 (US10155760, Example 123 | (S)-1-((2′,6-bis(d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Broad substrate specificity ATP-binding cassette transporter ABCG2 (Human)	BDBM311267 (US10155760, Example 123 | (S)-1-((2′,6-bis(d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent noradrenaline transporter (Human)	BDBM311267 (US10155760, Example 123 | (S)-1-((2′,6-bis(d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
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BMP-2-inducible protein kinase (Human)	BDBM311267 (US10155760, Example 123 | (S)-1-((2′,6-bis(d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Solute carrier organic anion transporter family member 1B1 (Human)	BDBM311267 (US10155760, Example 123 | (S)-1-((2′,6-bis(d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Citron Rho-interacting kinase (Human)	BDBM311267 (US10155760, Example 123 | (S)-1-((2′,6-bis(d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase LATS2 (Human)	BDBM311267 (US10155760, Example 123 | (S)-1-((2′,6-bis(d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
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MAP kinase-interacting serine/threonine-protein kinase 1 (Human)	BDBM311267 (US10155760, Example 123 | (S)-1-((2′,6-bis(d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM311267 (US10155760, Example 123 | (S)-1-((2′,6-bis(d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM311267 (US10155760, Example 123 | (S)-1-((2′,6-bis(d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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AP2-associated protein kinase 1 (Human)	BDBM311267 (US10155760, Example 123 | (S)-1-((2′,6-bis(d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
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AP2-associated protein kinase 1 (Human)	BDBM311267 (US10155760, Example 123 | (S)-1-((2′,6-bis(d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
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AP2-associated protein kinase 1 (Human)	BDBM311267 (US10155760, Example 123 | (S)-1-((2′,6-bis(d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM311267 (US10155760, Example 123 | (S)-1-((2′,6-bis(d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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AP2-associated protein kinase 1 (Human)	BDBM311267 (US10155760, Example 123 | (S)-1-((2′,6-bis(d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Human)	BDBM311267 (US10155760, Example 123 | (S)-1-((2′,6-bis(d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Human)	BDBM311267 (US10155760, Example 123 | (S)-1-((2′,6-bis(d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Human)	BDBM311267 (US10155760, Example 123 | (S)-1-((2′,6-bis(d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Human)	BDBM311267 (US10155760, Example 123 | (S)-1-((2′,6-bis(d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Human)	BDBM311267 (US10155760, Example 123 | (S)-1-((2′,6-bis(d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
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AP2-associated protein kinase 1 (Human)	BDBM311267 (US10155760, Example 123 | (S)-1-((2′,6-bis(d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM311267 (US10155760, Example 123 | (S)-1-((2′,6-bis(d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM311267 (US10155760, Example 123 | (S)-1-((2′,6-bis(d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Human)	BDBM311267 (US10155760, Example 123 | (S)-1-((2′,6-bis(d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM311267 (US10155760, Example 123 | (S)-1-((2′,6-bis(d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM311267 (US10155760, Example 123 | (S)-1-((2′,6-bis(d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2B6 (Human)	BDBM311267 (US10155760, Example 123 | (S)-1-((2′,6-bis(d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM311267 (US10155760, Example 123 | (S)-1-((2′,6-bis(d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Human)	BDBM311267 (US10155760, Example 123 | (S)-1-((2′,6-bis(d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Human)	BDBM311267 (US10155760, Example 123 | (S)-1-((2′,6-bis(d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Human)	BDBM311267 (US10155760, Example 123 | (S)-1-((2′,6-bis(d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM311267 (US10155760, Example 123 | (S)-1-((2′,6-bis(d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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