BDBM311793 2-Cyclopropyl-8-(7-methyl-1H-indazol-5-yl)-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridine::US10155769, Example 31

SMILES Cc1cc(cc2cn[nH]c12)-c1c(ccn2nc(nc12)C1CC1)C(F)(F)F

InChI Key InChIKey=MEIUEUQZTNMVBI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 311793   

TargetVoltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM311793(2-Cyclopropyl-8-(7-methyl-1H-indazol-5-yl)-7-(trif...)
Affinity DataIC50:  0.200nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent