BDBM31182 thiazol-2-amine, 13

SMILES Cc1ccccc1-c1csc(N)n1

InChI Key InChIKey=LTKJVQJOAXVWNL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 31182   

TargetRunt-related transcription factor 1(Homo sapiens (Human))
University Of Virginia At Charlottesville

LigandPNGBDBM31182(thiazol-2-amine, 13)
Affinity DataIC50:  3.30E+3nMAssay Description:His6-CBFbeta (1-141) was expressed and purified with the exception of the protease cleavage step. Cerulean-Runt domain fusion protein (Runx1 41-190) ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University Of Virginia At Charlottesville

LigandPNGBDBM31182(thiazol-2-amine, 13)
Affinity DataIC50:  5.00E+3nMpH: 7.5 T: 2°CAssay Description:For the FRET measurements, the Cerulean-Runt (Runx1 41-190) and Venus-CBFbeta (1-141) fusion proteins were dialyzed into FRET assay buffer. Protein c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed