BDBM311844 8-(7-Chloro-1H-indazol-5-yl)-2-cyclopropyl-3-fluoro-7-(trifluoromethyl)imidazo[1,2-c]pyrimidine::US10155769, Example 82

SMILES Fc1c(nc2c(-c3cc(Cl)c4[nH]ncc4c3)c(ncn12)C(F)(F)F)C1CC1

InChI Key InChIKey=BYGSYURHBBKYPY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 311844   

TargetVoltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM311844(8-(7-Chloro-1H-indazol-5-yl)-2-cyclopropyl-3-fluor...)
Affinity DataIC50:  0.316nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent