BDBM31202 JMC493432 Compound 8::MI-63
SMILES CC(C)(C)C[C@H]1N[C@H]([C@H](c2cccc(Cl)c2F)[C@@]11C(=O)Nc2cc(Cl)ccc12)C(=O)NCCN1CCOCC1
InChI Key InChIKey=YTBYOWZWBDYLQF-BGLPIVGWSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 31202
Affinity DataKi: 1.70nMAssay Description:Inhibition of his-tagged human recombinant MDM2 binding to p53-based peptide PMDM6-F by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 3nM ΔG°: -11.5kcal/molepH: 7.5 T: 2°CAssay Description:The dose-dependent binding experiments were carried out with serial dilutions of the tested compounds in DMSO. A 5 ul sample of the tested samples an...More data for this Ligand-Target Pair
Affinity DataIC50: 28.3nMAssay Description:Inhibition of his-tagged human recombinant MDM2 binding to p53-based peptide PMDM6-F by fluorescence polarization assayMore data for this Ligand-Target Pair