BDBM312188 6-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)butoxy)-2H-benzo[b][1,4]oxazin-3(4H)-one::US10441590, Compound B::US12053477, Compound A::US9604944, 15b (Example 14)::US9975862, 15b (Example 14)

SMILES: Clc1cccc(N2CCN(CCCCOc3ccc4OCC(=O)Nc4c3)CC2)c1Cl

InChI Key: InChIKey=PMKMNTBZJOXTJW-UHFFFAOYSA-N

Data: 18 KI  6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 21 hits for monomerid = 312188   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Human)	BDBM312188 (US9604944, 15b (Example 14) | 6-(4-(4-(2,3-Dichlor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.96	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Human)	BDBM312188 (US9604944, 15b (Example 14) | 6-(4-(4-(2,3-Dichlor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.25	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM312188 (US9604944, 15b (Example 14) | 6-(4-(4-(2,3-Dichlor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2B (Human)	BDBM312188 (US9604944, 15b (Example 14) | 6-(4-(4-(2,3-Dichlor...) Show SMILES Show InChI	GoogleScholar	UniChem		0.190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM312188 (US9604944, 15b (Example 14) | 6-(4-(4-(2,3-Dichlor...) Show SMILES Show InChI	GoogleScholar	UniChem		0.190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM312188 (US9604944, 15b (Example 14) | 6-(4-(4-(2,3-Dichlor...) Show SMILES Show InChI	GoogleScholar	UniChem		0.610	n/a	1.96	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM312188 (US9604944, 15b (Example 14) | 6-(4-(4-(2,3-Dichlor...) Show SMILES Show InChI	GoogleScholar	UniChem		0.610	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM312188 (US9604944, 15b (Example 14) | 6-(4-(4-(2,3-Dichlor...) Show SMILES Show InChI	GoogleScholar	UniChem		0.620	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM312188 (US9604944, 15b (Example 14) | 6-(4-(4-(2,3-Dichlor...) Show SMILES Show InChI	GoogleScholar	UniChem		0.620	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM312188 (US9604944, 15b (Example 14) | 6-(4-(4-(2,3-Dichlor...) Show SMILES Show InChI	GoogleScholar	UniChem		1.5	n/a	2.25	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM312188 (US9604944, 15b (Example 14) | 6-(4-(4-(2,3-Dichlor...) Show SMILES Show InChI	GoogleScholar	UniChem		1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM312188 (US9604944, 15b (Example 14) | 6-(4-(4-(2,3-Dichlor...) Show SMILES Show InChI	GoogleScholar	UniChem		1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM312188 (US9604944, 15b (Example 14) | 6-(4-(4-(2,3-Dichlor...) Show SMILES Show InChI	GoogleScholar	UniChem		1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM312188 (US9604944, 15b (Example 14) | 6-(4-(4-(2,3-Dichlor...) Show SMILES Show InChI	GoogleScholar	UniChem		2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM312188 (US9604944, 15b (Example 14) | 6-(4-(4-(2,3-Dichlor...) Show SMILES Show InChI	GoogleScholar	UniChem		2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 7 (Human)	BDBM312188 (US9604944, 15b (Example 14) | 6-(4-(4-(2,3-Dichlor...) Show SMILES Show InChI	GoogleScholar	UniChem		2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Human)	BDBM312188 (US9604944, 15b (Example 14) | 6-(4-(4-(2,3-Dichlor...) Show SMILES Show InChI	GoogleScholar	UniChem		2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 6 (Human)	BDBM312188 (US9604944, 15b (Example 14) | 6-(4-(4-(2,3-Dichlor...) Show SMILES Show InChI	GoogleScholar	UniChem		51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Human)	BDBM312188 (US9604944, 15b (Example 14) | 6-(4-(4-(2,3-Dichlor...) Show SMILES Show InChI	GoogleScholar	UniChem		51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM312188 (US9604944, 15b (Example 14) | 6-(4-(4-(2,3-Dichlor...) Show SMILES Show InChI	GoogleScholar	UniChem		58.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM312188 (US9604944, 15b (Example 14) | 6-(4-(4-(2,3-Dichlor...) Show SMILES Show InChI	GoogleScholar	UniChem		58.5	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair