BDBM312201 US9604926, Compound CM-396::US9724435, Compound CM-396
SMILES Cn1c2ccccc2n(CCCCN2CCN(CC2)C2CCCCC2)c1=O
InChI Key InChIKey=WSCMDSDVNPOTBT-UHFFFAOYSA-N
Data 6 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 312201
Affinity DataKi: 2.57nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
Affinity DataKi: 2.57nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Displacement of [3H]-DTG from sigma2 receptor in rat brain membranes after 120 mins in presence of (+)-pentazocine by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in rat brain membranes after 120 mins by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 50.2nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi
US Patent
The University Of Mississippi
US Patent
Affinity DataKi: 50.2nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair