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BDBM312236 US9604926, Compound AZ-81::US9724435, Compound AZ-81

SMILES: Fc1ccc2nc(SCCCCN3CCN(CC3)C3CCCCC3)sc2c1

InChI Key: InChIKey=AGDUPRGRBJBLDA-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 312236   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sigma-2 receptor


(Rattus norvegicus (Rat))
BDBM312236
PNG
(US9604926, Compound AZ-81 | US9724435, Compound AZ...)
Show SMILES Fc1ccc2nc(SCCCCN3CCN(CC3)C3CCCCC3)sc2c1
Show InChI InChI=1S/C21H30FN3S2/c22-17-8-9-19-20(16-17)27-21(23-19)26-15-5-4-10-24-11-13-25(14-12-24)18-6-2-1-3-7-18/h8-9,16,18H,1-7,10-15H2
UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
13.8n/an/an/an/an/an/an/an/a



The University of Mississippi

US Patent


Assay Description
Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...


US Patent US9724435 (2017)


BindingDB Entry DOI: 10.7270/Q2BZ6856
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Mus musculus (Mouse))
BDBM312236
PNG
(US9604926, Compound AZ-81 | US9724435, Compound AZ...)
Show SMILES Fc1ccc2nc(SCCCCN3CCN(CC3)C3CCCCC3)sc2c1
Show InChI InChI=1S/C21H30FN3S2/c22-17-8-9-19-20(16-17)27-21(23-19)26-15-5-4-10-24-11-13-25(14-12-24)18-6-2-1-3-7-18/h8-9,16,18H,1-7,10-15H2
UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
13.8n/an/an/an/an/an/an/an/a



The University of Mississippi

US Patent


Assay Description
Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...


US Patent US9604926 (2017)


BindingDB Entry DOI: 10.7270/Q27D2X6J
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Mus musculus (Mouse))
BDBM312236
PNG
(US9604926, Compound AZ-81 | US9724435, Compound AZ...)
Show SMILES Fc1ccc2nc(SCCCCN3CCN(CC3)C3CCCCC3)sc2c1
Show InChI InChI=1S/C21H30FN3S2/c22-17-8-9-19-20(16-17)27-21(23-19)26-15-5-4-10-24-11-13-25(14-12-24)18-6-2-1-3-7-18/h8-9,16,18H,1-7,10-15H2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
14.3n/an/an/an/an/an/an/an/a



The University of Mississippi

US Patent


Assay Description
Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...


US Patent US9604926 (2017)


BindingDB Entry DOI: 10.7270/Q27D2X6J
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)
BDBM312236
PNG
(US9604926, Compound AZ-81 | US9724435, Compound AZ...)
Show SMILES Fc1ccc2nc(SCCCCN3CCN(CC3)C3CCCCC3)sc2c1
Show InChI InChI=1S/C21H30FN3S2/c22-17-8-9-19-20(16-17)27-21(23-19)26-15-5-4-10-24-11-13-25(14-12-24)18-6-2-1-3-7-18/h8-9,16,18H,1-7,10-15H2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
14.3n/an/an/an/an/an/an/an/a



The University of Mississippi

US Patent


Assay Description
Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...


US Patent US9724435 (2017)


BindingDB Entry DOI: 10.7270/Q2BZ6856
More data for this
Ligand-Target Pair