BDBM312405 2-[6,6-Difluoro-3-(4-methyl-thiazol-2-yl)-4,5,6,7-tetrahydro-benzo[b]thiophen-2-ylcarbamoyl]-cyclohex-1-enecarboxylic acid::US9604977, Example 151

SMILES Cc1csc(n1)-c1c(NC(=O)C2=C(CCCC2)C(O)=O)sc2CC(F)(F)CCc12

InChI Key InChIKey=NPVHKMDUSWYEPY-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 312405   

TargetFatty acid-binding protein 5(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM312405(2-[6,6-Difluoro-3-(4-methyl-thiazol-2-yl)-4,5,6,7-...)
Affinity DataIC50:  20nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetFatty acid-binding protein, adipocyte(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM312405(2-[6,6-Difluoro-3-(4-methyl-thiazol-2-yl)-4,5,6,7-...)
Affinity DataIC50:  30nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB