BDBM312502 2-{2-[(2-Carboxy-cyclopent-1-enecarbonyl)-amino]-6,6-difluoro-4,5,6,7-tetrahydro-benzo[b]thiophen-3-yl}-thiazole-4-carboxylic acid ethyl ester::US9604977, Example 248

SMILES CCOC(=O)c1csc(n1)-c1c(NC(=O)C2=C(CCC2)C(O)=O)sc2CC(F)(F)CCc12

InChI Key InChIKey=BGBGUHLURLZALF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 312502   

TargetFatty acid-binding protein, adipocyte(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM312502(US9604977, Example 248 | 2-{2-[(2-Carboxy-cyclopen...)
Affinity DataIC50: 261nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM312502(US9604977, Example 248 | 2-{2-[(2-Carboxy-cyclopen...)
Affinity DataIC50: 1.93E+3nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent