BDBM312517 2-[4-(1-Aminocyclobutyl)phenyl]-3-phenylimidazo[1,2-b]pyridazine-6-carboxamide::US9604989, Example 5

SMILES: NC(=O)c1ccc2nc(c(-c3ccccc3)n2n1)-c1ccc(cc1)C1(N)CCC1

InChI Key: InChIKey=JBGYKRAZYDNCNV-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 312517   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase (Human)	BDBM312517 (US9604989, Example 5 | 2-[4-(1-Aminocyclobutyl)phe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
RAC-beta serine/threonine-protein kinase (Human)	BDBM312517 (US9604989, Example 5 | 2-[4-(1-Aminocyclobutyl)phe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Human)	BDBM312517 (US9604989, Example 5 | 2-[4-(1-Aminocyclobutyl)phe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
RAC-beta serine/threonine-protein kinase (Human)	BDBM312517 (US9604989, Example 5 | 2-[4-(1-Aminocyclobutyl)phe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
RAC-gamma serine/threonine-protein kinase (Human)	BDBM312517 (US9604989, Example 5 | 2-[4-(1-Aminocyclobutyl)phe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair