BDBM31340 2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin-3-yl)oxyanilino]quinazolin-6-yl]prop-2-enyl]acetamide::2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]anilino]-6-quinazolinyl]prop-2-enyl]acetamide::2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-methyl-3-pyridyl)oxy]anilino]quinazolin-6-yl]allyl]acetamide::2-methoxy-N-[(E)-3-[4-[[3-methyl-4-(6-methylpyridin-3-yl)oxy-phenyl]amino]quinazolin-6-yl]prop-2-enyl]ethanamide::CHEMBL483321::CP-724714::cid_9874913

SMILES: COCC(=O)NC\C=C\c1ccc2ncnc(Nc3ccc(Oc4ccc(C)nc4)c(C)c3)c2c1

InChI Key: InChIKey=LLVZBTWPGQVVLW-UHFFFAOYSA-N

Data: 8 IC50  337 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 348 hits for monomerid = 31340   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 19 (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
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Cyclin-dependent kinase 8 (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.30E+3	n/a	n/a	n/a	7.4	23
TBA									Citation and Details
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Epidermal growth factor receptor [G719C] (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	10	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
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MAP kinase-interacting serine/threonine-protein kinase 2 (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	840	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	720	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [1-999,L858R] (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.10E+5	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Ferrochelatase, mitochondrial [R115L] (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 8 (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 8 (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Interleukin-1 receptor-associated kinase 3 (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Ribosomal protein S6 kinase alpha-2 (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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cGMP-dependent protein kinase 1 (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Myotonin-protein kinase (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Death-associated protein kinase 3 (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Aurora kinase B (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Fibroblast growth factor receptor 3 (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Serine/threonine-protein kinase B-raf (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Mast/stem cell growth factor receptor Kit (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Ribosomal protein S6 kinase alpha-5 (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Serine/threonine-protein kinase D2 (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM31340 (CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair